Salmonella: the young person would protect against food poisoning

Fasting would not only keep the line… but it would also protect against food poisoning such as salmonellosis. These are the findings of the new study conducted by the University of British Columbia.

Gwyneth Paltrow, Jennifer Aniston, Hugh Jackman, Delphine Wespiser… very many stars have adopted fasting, assuring that it allowed them to keep the line and feel better in their body. This does not seem to be the only benefit of this practice. A study, conducted by researchers at the University of British Columbia and published in the journal PLOS Pathogens on August 5, 2021, suggests that it protects against food poisoning.

Food poisoning: fewer symptoms with fasting

Scientists have come to the conclusion that fasting before and during exposure to salmonella reduces the risk of developing food poisoning after observing infected mice. During this experiment, rodents were deprived of solid foods for a period of 48 hours before and during an oral infection with the bacterium Salmonella enterica serotype Typhimurium. This pathogen causes, among other things, salmonellosis in humans.

Mice that fasted showed fewer signs of bacterial infection compared to those that were fed. Among other things, the team noticed that they had almost no damage and inflammation in the intestinal tissues. In contrast, when fasting animals were recharged for a day, a dramatic increase in salmonella was observed, although the infection is still attenuated compared to normal.

The beneficial effect of fasting was verified only if the animals had been infected orally. Symptoms were no less severe in those who came into contact with the bacteria intravenously. It is stated in the scientific article: “analyses of mouse microbiomes have shown significant changes associated with fasting and protection against infections”.

Caloric restriction: its beneficial effect is not limited to Salmonella

The Canadian researchers specify in their study that similar results were recorded with the bacterium Campylobacter jejuni, responsible for campylobacteriosis. This disease also of food origin has symptoms close to the intestinal flu (diarrhea, abdominal pain, fever, nausea …). They usually appear 2 to 5 days after infection and last up to ten days.

“These data suggest that therapeutic fasting or caloric restriction has the potential to act beneficially on infectious and potentially non-infectious gastrointestinal diseases,” the experts say. They then add: “Our research highlights the important role that food plays in regulating interactions between the host, enteric pathogens, and the intestinal microbiome. When food is limited, the microbiome appears to sequester the remaining nutrients, preventing pathogens from acquiring the energy they need to infect the host.”

The team acknowledges that further work is needed to confirm their discovery, but believes that “fasting or adjustment of dietary intake could be exploited for therapeutic purposes to treat infectious diseases in the future”.

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